Topic
Counterion content
TFA versus acetate salt, what it does to the mass balance, and why an honest 10mg vial can weigh 11.4mg of powder.
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2024-02first seen
2026-06last seen
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mg_per_mlthis gets repeated a lot so what is the counterion situation on these usually#other-peptides · 2024-02-17gradient_gregthis gets repeated a lot so counterion matters more on the short peptides because the counterion mass fraction is a bigger…#other-peptides · 2024-03-31slow.tapercounterion is a bigger share#other-peptides · 2024-04-20step_one_sianfor the sceptics counterion matters more on the short peptides because the counterion mass fraction is a bigger share, this…#other-peptides · 2024-04-27tenpencebrilliant, counterion is a bigger share#other-peptides · 2024-05-04lot_number_louperfect thanks, counterion matters more here#other-peptides · 2024-06-01two_four_ceilingis the counterion question genuinely bigger for the small ones, asking because two people told me different things#other-peptides · 2024-06-21forty_unitsstrict rule i keep the counterion fraction matters more on the small ones because it is a bigger share of the mass in the…#other-peptides · 2024-06-21aliquot_adamixed news counterion matters more on the short peptides because the counterion mass fraction is a bigger share, not a clinician#other-peptides · 2024-07-07void_volumeabout the date on these what does net peptide content mean next to gross mass#coa-reading · 2024-07-13vialkeepergood grief, counterion is a bigger share#other-peptides · 2024-07-14food_noise_offpinning this mentally the counterion fraction matters more on the small ones because it is a bigger share of the mass in the…#other-peptides · 2024-07-20forty_unitsis the counterion question genuinely bigger for the small ones#other-peptides · 2024-07-20logrotateevidence check is the counterion question genuinely bigger for the small ones, anyone at all#other-peptides · 2024-08-03half_life_halwhat is the counterion situation on these usually, asking because two people told me different things#other-peptides · 2024-08-11u100_patnet peptide is gross mass minus water minus counterion. that is why 11.4mg of powder can be a correct 10mg vial#coa-reading · 2024-08-18mg_per_mlis the counterion question genuinely bigger for the small ones, first time doing this#other-peptides · 2024-08-24warsaw_vialin what sense, counterion is a bigger share#other-peptides · 2024-09-06peak_splitcounterion is a bigger share#other-peptides · 2024-09-07HPLC_Hankthe counterion being unstated matters most where the counterion is a big fraction of the mass, take that with a pinch of salt.…#coa-reading · 2024-09-20HPLC_Hankhow much does the counterion being unstated actually matter, idle question#coa-reading · 2024-09-20truncation_truevidence question counterion matters more on the short peptides because the counterion mass fraction is a bigger share#other-peptides · 2024-09-22relabel_watchnot sure i follow, counterion matters more here#other-peptides · 2024-09-22sulphur_burpgross powder mass is not net peptide. water and counterion are in that number#reconstitution · 2024-10-04gradient_gregcounterion matters more on the short peptides because the counterion mass fraction is a bigger share, a supplier page is not a…#other-peptides · 2024-10-06satiety_sigsame here, counterion matters more here#other-peptides · 2024-10-06blank_runthe counterion fraction matters more on the small ones because it is a bigger share of the mass in the vial, thats one person,…#other-peptides · 2024-10-12salt_bridgefor anyone doing their first one gross powder mass is not net peptide. water and counterion are in that number, measure twice,…#reconstitution · 2024-10-16still_here_2024counterion matters more on the short peptides because the counterion mass fraction is a bigger share#other-peptides · 2024-10-23noct.titratetfa counterion runs higher by mass than acetate. if the certificate does not say, you cannot do the mass balance. weigh the vial#coa-reading · 2024-10-26meal_prep_mickthe counterion being unstated matters most where the counterion is a big fraction of the mass, three way match first#coa-reading · 2024-10-26blank_runabout the date on these how much does the counterion being unstated actually matter — and if water content is missing can i…#coa-reading · 2024-11-01ruo_onlywhat is the counterion situation on these usually, or is the pinned answer still current#other-peptides · 2024-11-04eight_mmbaseline month done counterion matters more on the short peptides because the counterion mass fraction is a bigger share#other-peptides · 2024-11-04hair_month_fourgutted for you#other-peptides · 2024-11-08deadspacethis gets repeated a lot so the counterion fraction matters more on the small ones because it is a bigger share of the mass in…#other-peptides · 2024-11-09bolus_bois the counterion question genuinely bigger for the small ones, context if you need it#other-peptides · 2024-11-10surpass_twoprobably a stupid question but tfa or acetate, how do i tell from the paperwork, whenever someone has a minute#coa-reading · 2024-11-17HPLC_Hankabout the date on these the counterion being unstated matters most where the counterion is a big fraction of the mass#coa-reading · 2024-11-25plateau_pengross powder mass is not net peptide. water and counterion are in that number, others may differ#reconstitution · 2024-12-12karl_fischerunstacked and learned something counterion matters more on the short peptides because the counterion mass fraction is a bigger…#other-peptides · 2024-12-14factory_direct_fifair point#coa-reading · 2025-01-04HPLC_Hankthe counterion being unstated matters most where the counterion is a big fraction of the mass, take that with a pinch of salt.…#coa-reading · 2025-01-04HPLC_Hankthats the counterion#coa-reading · 2025-01-05HPLC_Hankhow much does the counterion being unstated actually matter#coa-reading · 2025-01-05reship_ritacounterion matters more on the short peptides because the counterion mass fraction is a bigger share, i have it written down…#other-peptides · 2025-01-10lean_mass_lexwhat is the counterion situation on these usually, asking for the log#other-peptides · 2025-01-10per_mg_peteabout the counterion thing again is the counterion question genuinely bigger for the small ones#other-peptides · 2025-01-11per_mg_peteon preclinical meaning preclinical what is the counterion situation on these usually, sorry if thats been covered#other-peptides · 2025-01-11step_one_siancounterion matters more on the short peptides because the counterion mass fraction is a bigger share, that traces to one…#other-peptides · 2025-01-11karl_fischerfor the newer people gross powder mass is not net peptide. water and counterion are in that number, that is the whole trick…#reconstitution · 2025-01-12split_the_costthe counterion is not stated anywhere. how much does that change the arithmetic#coa-reading · 2025-01-13slow.taperhow much does the counterion being unstated actually matter — and is a certificate from the manufacturer ever worth more than…#coa-reading · 2025-01-17slow.tapernoticed something on a cert what does net peptide content mean next to gross mass, happy to be told to read the pin — and how…#coa-reading · 2025-01-17deamidationnet peptide content is what you are buying and gross mass is what you are weighing. the gap is water and counterion#coa-reading · 2025-01-18private_script_prievidence check what is the counterion situation on these usually, or have i misread it#other-peptides · 2025-01-21vat_on_importcounterion matters more here#other-peptides · 2025-01-23cold_chain_cmdrabout the date on these tfa or acetate, how do i tell from the paperwork, anyone — and is a batch level certificate ever…#coa-reading · 2025-01-26invoice_mismatchnet peptide is gross mass minus water minus counterion. that is why 11.4mg of powder can be a correct 10mg vial, that is a…#coa-reading · 2025-01-27cat_on_the_traycomparing a cert to an assay how much does the counterion being unstated actually matter, first time doing this#coa-reading · 2025-01-27